Alexa Hinojosa Ortiz
Síntesis profesional
Estudiante entusiasta y comprometida, con facilidad para trabajar en equipo y seguir lineamientos específicos. Busco integrarme a un entorno laboral retador y dinámico donde pueda adquirir experiencia en distintas áreas y fortalecer mis competencias profesionales.
Información general
3
3
years of professional experience
Experiencia laboral
Research Intern
Harvard Medical School
Boston, MA
2024.07 - 2025.07
- Company Overview: Research Intern in Brigham and Women’s hospital, Harvard Medical School, MIT
- Synthesis and Assessment of Novel RNA-loaded Lipid Nanoparticles and Microneedle delivery platforms for Gene Therapy.
- Characterized and assessed 20-formulation anti-inflammatory LNP library for transdermal gene therapy, optimizing PEG, DOTAP, and ionizable lipid composition to improve gene expression and cell viability for treating autoimmune conditions and transplant rejection.
- Engineered microneedle platforms incorporating LNPs for minimally invasive gene delivery targeting skin-resident immune cells.
- Evaluated over 30 lipid formulations in PEG-based microneedles to improve nanoparticle stability, bioavailability and transdermal delivery efficiency.
- In vitro evaluation of a triple-Chemoimmunotherapy from Injectable Hydrogels for Brain Cancer Therapy.
- Established a protocol to reproducibly culture 3D murine Glioblastoma (CT-2A) spheroids, for in vitro treatment with a Combination chemoimmunotherapy with DOX, STING agonist (CDNs), and anti-PD-1.
- Implemented image analysis automation coding using Image J.
- Performed isolation and maintenance of primary immune cells and maintaining them including macrophages, NK cells, T cells, and dendritic cells, for flow cytometry, functional assays, and co-culture experiments.
- Analyzed the particle transfer effect (PTE) between CT2A murine glioblastoma cells and macrophages using model nanoparticles to characterize intercellular nanoparticle trafficking within the tumor–immune microenvironment.
- Research Intern in Brigham and Women’s hospital, Harvard Medical School, MIT
- Poster presentation at 2nd Annual Gene and Cell Therapy Research Symposium Harvard Medical School & Brigham and Women’s Hospital. Boston, MA – November 2024. A. Hinojosa, S. Chohmalian, M.Z. Dion, N. Artzi. Transdermal Delivery of Nucleic Acids via the Optimization of Lipid Nanoparticle Loaded Microneedles for Therapeutic Applications.
The Center for Research and Assistance in Technology and Design of the State of Jalisco, A. (CIATEJ)
2024.02 - 2024.06
- Evaluation of cell viability of the Litocol oleate treatment on Vero cells for the determination of in vitro antiviral activity against VHS-1 using flow cytometry, RT-PCR, cytotoxicity assays and microscopic analysis.
The Institute for Obesity Research, Tec de Monterrey
2023.10 - 2024.06
- Therapeutic evaluation of phenolic compounds found in food.
- Implementation of metabolic assays of lipids and data analysis of cytotoxicity, anti-inflammatory and antioxidant activity.
Agencia Metropolitana de Bosques Urbanos (AMBU)
Guadalajara
2023.07 - 2023.10
- Development, design, and implementation of a sustainable biotechnology-based micropropagation protocol for the conservation of the endangered native plant species Ficus Petiolaris Kunth in Jalisco, Mexico.
Project leader
2023.01 - 2023.08
- Formulation of biofertilizers from nitrifying bacteria and growth-promoting rhizobacteria.
- Isolated and identified native PGPR (plant growth-promoting rhizobacteria) from agricultural soils in southern Jalisco using bacterial culture techniques and PCR-based molecular identification.
- Participated in the BIOHACKATON bio-entrepreneurship competition and presented a scientific poster at EXPOINGENIERÍAS, both held at Tecnológico de Monterrey.
VISTA (Visiting Students Association at MIT)
2025.02 - 2025.07
- Company Overview: Massachusetts Institute of Technology (MIT)
- As a board member and part of the communications team, created digital content, promoted events, co-organized and worked collaboratively with an international, multidisciplinary team to foster a welcoming and inclusive environment for visiting students at MIT.
- Massachusetts Institute of Technology (MIT)
Communication Leader
Women for the Future Program – Western Region
2022.02 - 2023.08
- Company Overview: Tec de Monterrey
- Represented the Western Region across four university campuses.
- Co-organized and supported the execution of two national leadership bootcamps (July 2022 and 2023) in collaboration with NGOs, universities, and private companies focused on empowering undergraduate women in STEM, entrepreneurship, and social impact.
- Tec de Monterrey
Unidad de Investigación de Salud (UIS)
2023.03 - 2023.07
- Contributed to gene therapy research for multiple sclerosis at Research in Human Health Company, utilizing pIRES2-EGFP vector and Sonic Hedgehog gene in vector expression design and production.
- In silico enhancement of the SHH gene and explored the use of nanoplasmids for efficient gene delivery.
Estudios
B.Sc. - Biotechnology Engineering
Instituto Tecnológico y de Estudios Superiores de Monterrey (Tecnológico de Monterrey)
Guadalajara, Jalisco, México12.2025
Competencias
- Advanced GraphPad Prism Analysis
- Advanced Zotero
- Image J
- Basic FlowJo
- Microsoft Excel
- LaTeX
- Basic MATLAB
- Intermediate Minitab
- Intermediate Benching
- Intermediate HTML Suite Office
- Basic Molecular docking on Chimera
- Problem solving
- Positive attitude and willingness to learn
- Critical thinking
- Strong leadership
- Teamwork
Sitios web
Awards
- Leader of tomorrow, eight generation, Awarded one of the most competitive full-tuition scholarships in Mexico.
- EGS Global Leadership Program, 3rd generation, Tec de Monterrey’s leadership program for undergraduate students.
- Hall Advisor, Selected as a hall advisor, providing support for residential life.
- Women Leaders in STEAM-National Participant, Selected in high school for a national program focused in STEM education.
Personalizado
- Playing the violin
- Painting
- Tennis
- Salsa dancing
Idiomas
Inglés
Idioma principal
Cronología
VISTA (Visiting Students Association at MIT)
2025.02 - 2025.07
Research Intern
Harvard Medical School
2024.07 - 2025.07
The Center for Research and Assistance in Technology and Design of the State of Jalisco, A. (CIATEJ)
2024.02 - 2024.06
The Institute for Obesity Research, Tec de Monterrey
2023.10 - 2024.06
Agencia Metropolitana de Bosques Urbanos (AMBU)
2023.07 - 2023.10
Unidad de Investigación de Salud (UIS)
2023.03 - 2023.07
Project leader
2023.01 - 2023.08
Communication Leader
Women for the Future Program – Western Region
2022.02 - 2023.08
B.Sc. - Biotechnology Engineering
Instituto Tecnológico y de Estudios Superiores de Monterrey (Tecnológico de Monterrey)