Brissia Lazalde

Committed and engaging professor in Faculty of Medicine bringing exceptional lecturing skills and department leadership experience with expertise in Medical Genetics. Inspiring Professor brings advanced teaching skills Goal-oriented to advance department, improve teaching and modernize courses.

Extensive background in research and university fundraising.

Patient-focused Physician specializing in Human Genetics, providing high quality, personal levels of healthcare to patients in Hospital clinical environments, with recognized medical skills resulting in 21 years of successful practice. Warm, caring approach to patients and persistent in finding diagnosis for rare diseases.

Journal Publications

1. Brissia Lazalde, Rocío Sánchez-Urbina, Ismael Nuño Arana, Wadih E. Bitar and María de Lourdes Ramírez-Dueñas. Autosomal Dominant Inheritance in Cantú Síndrome (Congenital Hypertrichosis, Osteochondrodysplasia, and Cardiomegaly). Am J Med Genet; 94:421-427. 2000.

2. Brissia Lazalde, Rocío Sánchez-Urbina, Javier E García de Alba G, María de Lourdes Ramírez-Dueñas. Diabetes Mellitus Gestacional y Malformaciones Congénitas. Ginecología y Obstetricia de México; 69:399-405. 2001.

3. Melva Gutierrez-Angulo*, Brissia Lazalde*, Ana I Vasquez, Caridad Leal, Elisa Corral, Horacio Rivera. Dynamic Mosaicism for a del(X)(p22.1) and r(X)(p22.1q28) in a patient with Turner syndrome. Annales de Gènètique; 45:17-20. 2002.

4. Miguel R. Reyes, Brissia Lazalde. Cell growth in vitro directed by handmade patterns. In Vitro Cell Dev. Biol.; 40:258-261. 2004.

5. Miguel R. Reyes, Antonio Sifuentes Álvarez, Brissia Lazalde. Estrogens are potentially the only steroids with an antioxidant role in pregnancy: In vitro evidence. Acta Obstetricia et Gynecologica Scandinavica; 85:1090-1093. 2006.

6. Raul A. Bastarrachea,* Jackw. Kent Jr.,* Guadalupe Rozada, Shelleya. Cole, Juan C. López-Alvarenga, Celia Aradillas, Olga Brito-Zurita, Ricardo M. Cerda-Flores, Emma Ibarra-Costilla, Esther Gallegos, Hugo Laviada, Victor Hernandez-Escalante, Juan Rosas, Anselmo Machado, Felipe Vadillo, Manuel Ramos, Brissia Lazalde, Jesus Santaolalla, Jeanw. Maccluer, Anthony G. Comuzzie. Heritability and Genetic Correlations of Metabolic Disease–Related Phenotypes in Mexico: Preliminary Report from the GEMM Family Study. Human Biology, 2007, 78: 121–130.

7. Miguel R. Reyes, Brissia Lazalde. Aortic preadipocyte differentiation into adipocytes induced by rosiglitazone in an in vitro model. In Vitro Cell Dev Biol Anim. 2007 May-Jun;43(5-6):159-61.

González-Arellano JA, Milla-Villeda RH, Hernández-Vera GE, Cisneros-Pérez V, Lazalde B, Reyes MR. [Prevalence of osteoporosis and osteopenia among women over fifty years of age, from the city of Durango, Mexico, diagnosed by forearm-DEXA] Gac Med Mex. 2007 Sep-Oct;143(5):365-9.

8. Reyes MR, Lazalde B, Posadas del Rio FA, Escalante B. Identification of leptin gene expression in sinusoidal endothelial rat liver cells. Endothelium. 2008 May-Jun; 15(3):121-5

9. Zambrano-Galvan G, Rodríguez-Morán M, Simental-Mendía LE, Lazalde B, Reyes-Romero MA, Guerrero-Romero F. C-reactive protein is directly associated with urinary albumin-to-creatinine ratio. Arch Med Res. 2011 Aug;42(6):451-6.Epub 2011 Sep 22. PubMed PMID: 21945876.

10. Brambila-Tapia AJ, Durán-González J, Sandoval-Ramírez L, Mena JP, Salazar-Páramo M, Gámez-Nava JI, González-López L, Lazalde-Medina B B, Dávalos NO, Peralta-Leal V, Del Mercado MV, Beltrán-Miranda CP, Dávalos IP. MTHFR C677T, MTHFR A1298C, and OPG A163G polymorphisms in Mexican patients with rheumatoid arthritis and osteoporosis. Dis Markers. 2012;32(2):109-14.

11. Nuño-Arana I, Sahagún-Núñez VD, Muñoz-Valle JF, Sandoval L, Pinto-Escalante D, Páez-Riberos LA, Lazalde B, Maldonado-González M, Rangel-Villalobos H. Distribution of three SNPs related to low bone mineral density in amerindian groups and mestizos from Mexico. Am J Hum Biol. 2012 Mar 21. doi:10.1002/ajhb.2226

12. Lazalde B, Grijalva-Flores J, Guerrero-Romero F. Klippel-Feil syndrome in a boy exposed inadvertently to cyclophosphamide during pregnancy: A case report. Birth Defects Res A Clin Mol Teratol. 2012 Apr; 94 (4):249-52. doi:10.1002/bdra.23004.

13. Simental-Mendía LE, Lazalde B, Zambrano-Galván G, Simental-Saucedo L, Rábago-Sánchez E, Rodríguez-Morán M, Guerrero-Romero F. Relation between C-reactive protein and impaired fasting glucose in obese subjects. Inflammation. 2012 Oct;35(5):1742-6. doi: 10.1007/s10753-012-9492-z.

14. Lazalde B, Huerta-Guerrero HM, Simental-Mendía LE, Rodríguez-Morán M, Guerrero-Romero F. Haptoglobin 2-2 genotype is associated with TNF- α and IL-6 levels in subjects with obesity. Dis Markers. 2014;2014:912756. doi: 10.1155/2014/912756. Epub 2014 Apr 29.

15. Zambrano-Galván G, Reyes-Romero MA, Lazalde B, Rodríguez-Morán M, Guerrero-Romero F. Risk of microalbuminuria in relatives of subjects with diabetic nephropathy: a predictive model based on multivariable dimensionality reduction approach. Clin Nephrol. 2015

16. Feb;83(2):86-92. doi: 10.5414/CN108395.

Velázquez-Hernández N, Reyes-Romero MA, Barragán-Hernández M, Guerrero-Romero F, Rodríguez-Moran M, Aguilar-Durán M, Lazalde Medina B. BORIS and CTCF are overexpressed in squamous intraepithelial lesions and cervical cancer. Genet Mol Res. 2015 Jun 10;14(2):6094-100. doi: 10.4238/2015.June.8.7.

17. Velazquez-Hernandez N, Aguilar-Duran M, Perez-Alamos AR, Estrada-Martinez S, Salas-Pacheco JM, Sanchez-Anguiano LF, Sandoval-Carrillo AA, Lazalde-Medina B, Alvarado-Esquivel C. Lack of Association between Mannose-binding Lectin 2 Codons 54 and 57 Gene Polymorphisms and Cervicovaginal Infections in Mexican Women. Int J Biomed Sci. 2017 Jun;13(2):79-83.

18. Lazalde B, Aguirre-Hernández G, González-Arreola R M, Venegas Rodríguez JL, Gonzalez Font AE . Novel premature termination codon mutation in FBN1 gene in an infant with severe Marfan syndrome. Curr Pediatr Res 2017; 21 (4): 541-545

19. Ivanovski I, Djuric O, Broccoli S, Caraffi SG, Accorsi P, Adam MP, Avela K, Badura-Stronka M, Bayat A, Clayton-Smith J, Cocco I, Cordelli DM, Cuturilo G, Di Pisa V, Dupont Garcia J, Gastaldi R, Giordano L, Guala A, Hoei-Hansen C, Inaba M, Iodice A, Nielsen JEK, Kuburovic V, Lazalde-Medina B, Malbora B, Mizuno S, Moldovan O, Møller RS, Muschke P, Otelli V, Pantaleoni C, Piscopo C, Poch-Olive ML, Prpic I, Marín Reina P, Raviglione F, Ricci E, Scarano E, Simonte G, Smigiel R, Tanteles G, Tarani L, Trimouille A, Valera ET, Schrier Vergano S, Writzl K, Callewaert B, Savasta S, Street ME, Iughetti L, Bernasconi S, Giorgi Rossi P, Garavelli L. Mowat-Wilson syndrome: growth charts. Orphanet J Rare Dis. 2020 Jun 15;15(1):151.

20. Lazalde B, Gurrola-Luna CJA, Gonzalez-Arreola RM, Velasco-Lazalde V and Rivera-Ayala M. Highly penetrant AUTS2 syndrome phenotype in a boy with AUTS2 C-terminal intragenic deletion. J Autism. 2022; 9:3. http://dx.doi.org/10.7243/2054-992X-9-3

Asociación Mexicana de Genética Humana

American Association of Human Genetics

European Association of Human Genetics